Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Genetic variation in both innate and adaptive immune systems is associated with Crohn's disease (CD) susceptibility, but much of the heritability to CD remains unknown. We performed a genome-wide association study (GWAS) in 896 CD cases and 3204 healthy controls all of Caucasian origin as defin...

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Autori principali: McGovern, Dermot P.B., Jones, Michelle R., Taylor, Kent D., Marciante, Kristin, Yan, Xiaofei, Dubinsky, Marla, Ippoliti, Andy, Vasiliauskas, Eric, Berel, Dror, Derkowski, Carrie, Dutridge, Deb, Fleshner, Phil, Shih, David Q., Melmed, Gil, Mengesha, Emebet, King, Lily, Pressman, Sheila, Haritunians, Talin, Guo, Xiuqing, Targan, Stephan R., Rotter, Jerome I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916706/
https://ncbi.nlm.nih.gov/pubmed/20570966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq248
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