IL-23 Receptor (IL-23R) Gene Protects Against Pediatric Crohn’s Disease

BACKGROUND: The IL-23 receptor (IL-23R) has been found to be associated with small bowel Crohn’s disease (CD) in a whole genome association study. Specifically, the rare allele of the R381Q single nucleotide polymorphism (SNP) conferred protection against CD. It is unknown whether IL-23R is associat...

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Autori principali: Dubinsky, Marla C., Wang, Dai, Picornell, Yoana, Wrobel, Iwona, Katzir, Lirona, Quiros, Antonio, Dutridge, Debra, Wahbeh, Ghassan, Silber, Gary, Bahar, Ron, Mengesha, Emebet, Targan, Stephan R., Taylor, Kent D., Rotter, Jerome I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169293/
https://ncbi.nlm.nih.gov/pubmed/17309073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20126
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