Increased Immune Reactivity Predicts Aggressive Complicating Crohn’s disease in Children

BACKGROUND AND AIM: The ability to identify children with Crohn’s disease who are at highest risk for rapid progression from uncomplicated to complicated phenotypes would be invaluable in guiding initial therapy. Aim: To determine whether immune responses and/or CARD15 variants are associated with c...

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Main Authors: Dubinsky, Marla C, Kugathasan, Subra, Mei, Ling, Picornell, Yoana, Nebel, Justin, Wrobel, Iwona, Quiros, Antonio, Silber, Gary, Wahbeh, Ghassan, Katzir, Lirona, Vasiliauskas, Eric, Bahar, Ron, Otley, Anthony, Mack, David, Evans, Jonathan, Rosh, Joel, Hemker, Maria Oliva, Leleiko, Neal, Crandall, Wallace, Langton, Christine, Landers, Carol, Taylor, Kent D., Targan, Stephan R, Rotter, Jerome I, Markowitz, James, Hyams, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745777/
https://ncbi.nlm.nih.gov/pubmed/18619921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2008.04.032
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