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IL23R Haplotypes Provide A Large Population Attributable Risk for Crohn’s Disease

The IL-23 pathway plays a pivotal role in the development of chronic mucosal inflammation seen in the inflammatory bowel diseases. Multiple studies have now established the contribution of the interleukin 23 receptor gene (IL23R) to Crohn’s Disease (CD) risk in general and of the IL23R R381Q variant...

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Détails bibliographiques
Auteurs principaux: Taylor, Kent D., Targan, Stephan R., Mei, Ling, Ippoliti, Andrew F., McGovern, Dermot, Mengesha, Emebet, King, Lily, Rotter, Jerome I.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574614/
https://ncbi.nlm.nih.gov/pubmed/18470928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.20478
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