Increased prevalence of inflammatory bowel disease in patients with mutations in genes encoding the receptor subunits for TGFβ

BACKGROUND: TGFβ is a multifunctional cytokine that is critical in regulating mucosal immunity. Murine studies have revealed that disruption of canonical TGFβ signaling leads to systemic inflammation including colitis. Loeys-Dietz syndrome (LDS) results from heterozygous mutations in the genes encod...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Guerrerio, Anthony L., Frischmeyer-Guerrerio, Pamela A., Huang, Chengrui, Wu, Yuqiong, Haritunians, Talin, McGovern, Dermot P.B., MacCarrick, Gretchen L., Brant, Steven R., Dietz, Harry C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992461/
https://ncbi.nlm.nih.gov/pubmed/27508510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000872
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados