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TGFβ Receptor Mutations Impose a Strong Predisposition for Human Allergic Disease

Transforming growth factor–β (TGFβ) is a multifunctional cytokine that plays diverse roles in physiologic processes as well as human disease, including cancer, heart disease, and fibrotic disorders. In the immune system, TGFβ regulates regulatory T cell (T(reg)) maturation and immune homeostasis. Al...

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Detalhes bibliográficos
Main Authors: Frischmeyer-Guerrerio, Pamela A., Guerrerio, Anthony L., Oswald, Gretchen, Chichester, Kristin, Myers, Loretha, Halushka, Marc K., Oliva-Hemker, Maria, Wood, Robert A., Dietz, Harry C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905327/
https://ncbi.nlm.nih.gov/pubmed/23884466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006448
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