Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates

per Nanty, Lisa, Carbajosa, Guillermo, Heap, Graham A., Ratnieks, Francis, van Heel, David A., Down, Thomas A., Rakyan, Vardhman K.
Publicat 2011

Complex nature of SNP genotype effects on gene expression in primary human leucocytes

per Heap, Graham A, Trynka, Gosia, Jansen, Ritsert C, Bruinenberg, Marcel, Swertz, Morris A, Dinesen, Lotte C, Hunt, Karen A, Wijmenga, Cisca, vanHeel, David A, Franke, Lude
Publicat 2009

Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

per Smyth, Deborah J, Plagnol, Vincent, Walker, Neil M, Cooper, Jason D, Downes, Kate, Yang, Jennie HM, Howson, Joanna MM, Stevens, Helen, McManus, Ross, Wijmenga, Cisca, Heap, Graham A., Dubois, Patrick C., Clayton, David G., Hunt, Karen A, van Heel, David A, Todd, John A
Publicat 2008

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing

per Heap, Graham A., Yang, Jennie H.M., Downes, Kate, Healy, Barry C., Hunt, Karen A., Bockett, Nicholas, Franke, Lude, Dubois, Patrick C., Mein, Charles A., Dobson, Richard J., Albert, Thomas J., Rodesch, Matthew J., Clayton, David G., Todd, John A., van Heel, David A., Plagnol, Vincent
Publicat 2010

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

per de Lange, Katrina M., Moutsianas, Loukas, Lee, James C., Lamb, Christopher A., Luo, Yang, Kennedy, Nicholas A., Jostins, Luke, Rice, Daniel L., Gutierrez-Achury, Javier, Ji, Sun-Gou, Heap, Graham, Nimmo, Elaine R., Edwards, Cathryn, Henderson, Paul, Mowat, Craig, Sanderson, Jeremy, Satsangi, Jack, Simmons, Alison, Wilson, David C., Tremelling, Mark, Hart, Ailsa, Mathew, Christopher G., Newman, William G., Parkes, Miles, Lees, Charlie W., Uhlig, Holm, Hawkey, Chris, Prescott, Natalie J., Ahmad, Tariq, Mansfield, John C., Anderson, Carl A., Barrett, Jeffrey C.
Publicat a Nat Genet (2017)

Novel celiac disease genetic determinants related to the immune response

per Hunt, Karen A, Zhernakova, Alexandra, Turner, Graham, Heap, Graham A.R., Franke, Lude, Bruinenberg, Marcel, Romanos, Jihane, Dinesen, Lotte C., Ryan, Anthony W, Panesar, Davinder, Gwilliam, Rhian, Takeuchi, Fumihiko, McLaren, William M, Holmes, Geoffrey KT, Howdle, Peter D, Walters, Julian RF, Sanders, David S, Playford, Raymond J, Trynka, Gosia, Mulder, Chris JJ, Mearin, M Luisa, Verbeek, Wieke HM, Trimble, Valerie, Stevens, Fiona M, O’Morain, Colm, Kennedy, Nicholas P, Kelleher, Dermot, Pennington, Daniel J, Strachan, David P, McArdle, Wendy L, Mein, Charles A, Wapenaar, Martin C, Deloukas, Panos, McGinnis, Ralph, McManus, Ross, Wijmenga, Cisca, van Heel, David A
Publicat 2008

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

per Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Publicat a Nat Commun (2016)

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease

per Walker, Gareth J., Harrison, James W., Heap, Graham A., Voskuil, Michiel D., Andersen, Vibeke, Anderson, Carl A., Ananthakrishnan, Ashwin N., Barrett, Jeffrey C., Beaugerie, Laurent, Bewshea, Claire M., Cole, Andy T., Cummings, Fraser R., Daly, Mark J., Ellul, Pierre, Fedorak, Richard N., Festen, Eleonora A. M., Florin, Timothy H., Gaya, Daniel R., Halfvarson, Jonas, Hart, Ailsa L., Heerasing, Neel M., Hendy, Peter, Irving, Peter M., Jones, Samuel E., Koskela, Jukka, Lindsay, James O., Mansfield, John C., McGovern, Dermot, Parkes, Miles, Pollok, Richard C. G., Ramakrishnan, Subramaniam, Rampton, David S., Rivas, Manuel A., Russell, Richard K., Schultz, Michael, Sebastian, Shaji, Seksik, Philippe, Singh, Abhey, So, Kenji, Sokol, Harry, Subramaniam, Kavitha, Todd, Anthony, Annese, Vito, Weersma, Rinse K., Xavier, Ramnik, Ward, Rebecca, Weedon, Michael N., Goodhand, James R., Kennedy, Nicholas A., Ahmad, Tariq
Publicat a JAMA (2019)

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

per Rivas, Manuel A., Avila, Brandon E., Koskela, Jukka, Huang, Hailiang, Stevens, Christine, Pirinen, Matti, Haritunians, Talin, Neale, Benjamin M., Kurki, Mitja, Ganna, Andrea, Graham, Daniel, Glaser, Benjamin, Peter, Inga, Atzmon, Gil, Barzilai, Nir, Levine, Adam P., Schiff, Elena, Pontikos, Nikolas, Weisburd, Ben, Lek, Monkol, Karczewski, Konrad J., Bloom, Jonathan, Minikel, Eric V., Petersen, Britt-Sabina, Beaugerie, Laurent, Seksik, Philippe, Cosnes, Jacques, Schreiber, Stefan, Bokemeyer, Bernd, Bethge, Johannes, Heap, Graham, Ahmad, Tariq, Plagnol, Vincent, Segal, Anthony W., Targan, Stephan, Turner, Dan, Saavalainen, Paivi, Farkkila, Martti, Kontula, Kimmo, Palotie, Aarno, Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Weersma, Rinse K., Franke, Andre, Jostins, Luke, Anderson, Carl A., Barrett, Jeffrey C., MacArthur, Daniel G., Jalas, Chaim, Sokol, Harry, Xavier, Ramnik J., Pulver, Ann, Cho, Judy H., McGovern, Dermot P. B., Daly, Mark J.
Publicat a PLoS Genet (2018)

HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

per Heap, Graham A, Weedon, Michael N, Bewshea, Claire M, Singh, Abhey, Chen, Mian, Satchwell, Jack B, Vivian, Julian P, So, Kenji, Dubois, Patrick C, Andrews, Jane M, Annese, Vito, Bampton, Peter, Barnardo, Martin, Bell, Sally, Cole, Andy, Connor, Susan J, Creed, Tom, Cummings, Fraser R, D'Amato, Mauro, Daneshmend, Tawfique K, Fedorak, Richard N, Florin, Timothy H, Gaya, Daniel R, Greig, Emma, Halfvarson, Jonas, Hart, Alisa, Irving, Peter M, Jones, Gareth, Karban, Amir, Lawrance, Ian C, Lee, James C, Lees, Charlie, Lev-Tzion, Raffi, Lindsay, James O, Mansfield, John, Mawdsley, Joel, Mazhar, Zia, Parkes, Miles, Parnell, Kirstie, Orchard, Timothy R, Radford-Smith, Graham, Russell, Richard K, Reffitt, David, Satsangi, Jack, Silverberg, Mark S, Sturniolo, Giacomo C, Tremelling, Mark, Tsianos, Epameinondas V, van Heel, David A, Walsh, Alissa, Watermeyer, Gill, Weersma, Rinse K, Zeissig, Sebastian, Rossjohn, Jamie, Holden, Arthur L, Ahmad, Tariq
Publicat a Nat Genet (2014)

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

per Rivas, Manuel A., Avila, Brandon E., Koskela, Jukka, Huang, Hailiang, Stevens, Christine, Pirinen, Matti, Haritunians, Talin, Neale, Benjamin M., Kurki, Mitja, Ganna, Andrea, Graham, Daniel, Glaser, Benjamin, Peter, Inga, Atzmon, Gil, Barzilai, Nir, Levine, Adam P., Schiff, Elena, Pontikos, Nikolas, Weisburd, Ben, Lek, Monkol, Karczewski, Konrad J., Bloom, Jonathan, Minikel, Eric V., Petersen, Britt-Sabina, Beaugerie, Laurent, Seksik, Philippe, Cosnes, Jacques, Schreiber, Stefan, Bokemeyer, Bernd, Bethge, Johannes, Heap, Graham, Ahmad, Tariq, Plagnol, Vincent, Segal, Anthony W., Targan, Stephan, Turner, Dan, Saavalainen, Paivi, Farkkila, Martti, Kontula, Kimmo, Palotie, Aarno, Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Weersma, Rinse K., Franke, Andre, Jostins, Luke, Anderson, Carl A., Barrett, Jeffrey C., MacArthur, Daniel G., Jalas, Chaim, Sokol, Harry, Xavier, Ramnik J., Pulver, Ann, Cho, Judy H., McGovern, Dermot P. B., Daly, Mark J.
Publicat a PLoS Genet (2019)

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

per Trynka, Gosia, Hunt, Karen A, Bockett, Nicholas A, Romanos, Jihane, Mistry, Vanisha, Szperl, Agata, Bakker, Sjoerd F, Bardella, Maria Teresa, Bhaw-Rosun, Leena, Castillejo, Gemma, de la Concha, Emilio G., de Almeida, Rodrigo Coutinho, Dias, Kerith-Rae M, van Diemen, Cleo C., Dubois, Patrick CA, Duerr, Richard H., Edkins, Sarah, Franke, Lude, Fransen, Karin, Gutierrez, Javier, Heap, Graham AR, Hrdlickova, Barbara, Hunt, Sarah, Izurieta, Leticia Plaza, Izzo, Valentina, Joosten, Leo AB, Langford, Cordelia, Mazzilli, Maria Cristina, Mein, Charles A, Midah, Vandana, Mitrovic, Mitja, Mora, Barbara, Morelli, Marinita, Nutland, Sarah, Núñez, Concepción, Onengut-Gumuscu, Suna, Pearce, Kerra, Platteel, Mathieu, Polanco, Isabel, Potter, Simon, Ribes-Koninckx, Carmen, Ricaño-Ponce, Isis, Rich, Stephen S., Rybak, Anna, Santiago, José Luis, Senapati, Sabyasachi, Sood, Ajit, Szajewska, Hania, Troncone, Riccardo, Varadé, Jezabel, Wallace, Chris, Wolters, Victorien M, Zhernakova, Alexandra, Thelma, B.K., Cukrowska, Bozena, Urcelay, Elena, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Barrett, Jeffrey C, Plagnol, Vincent, Deloukas, Panos, Wijmenga, Cisca, van Heel, David A
Publicat 2011

Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

per Hunt, Karen A, Smyth, Deborah J, Balschun, Tobias, Ban, Maria, Mistry, Vanisha, Ahmed, Tariq, Anand, Vidya, Barrett, Jeffrey C, Bhaw-Rosun, Leena, Bockett, Nicholas A, Brand, Oliver J, Brouwer, Elisabeth, Concannon, Patrick, Cooper, Jason D, Dias, Kerith-Rae M, van Diemen, Cleo C, Dubois, Patrick C, Edkins, Sarah, Fölster-Holst, Regina, Fransen, Karin, Glass, David N., Heap, Graham AR, Hofmann, Sylvia, Huizinga, Tom WJ, Hunt, Sarah, Langford, Cordelia, Lee, James, Mansfield, John, Marrosu, Maria Giovanna, Mathew, Christopher G, Mein, Charles A, Müller-Quernheim, Joachim, Nutland, Sarah, Onengut-Gumuscu, Suna, Ouwehand, Willem, Pearce, Kerra, Prescott, Natalie, Posthumus, Marcel D, Potter, Simon, Rosati, Giulio, Sambrook, Jennifer, Satsangi, Jack, Schreiber, Stefan, Shtir, Corina, Simmonds, Matthew J, Sudman, Marc, Thompson, Susan D, Toes, Rene, Trynka, Gosia, Vyse, Timothy J, Walker, Neil M, Weidinger, Stephan, Zhernakova, Alexandra, Zoledziewska, Magdalena, Weersma, Rinse K, Gough, Stephen CL, Sawcer, Stephen, Wijmenga, Cisca, Parkes, Miles, Cucca, Francesco, Franke, Andre, Deloukas, Panos, Rich, Stephen S., Todd, John A, van Heel, David A
Publicat 2011

Multiple common variants for celiac disease influencing immune gene expression

per Dubois, Patrick CA, Trynka, Gosia, Franke, Lude, Hunt, Karen A, Romanos, Jihane, Curtotti, Alessandra, Zhernakova, Alexandra, Heap, Graham AR, Ádány, Róza, Aromaa, Arpo, Bardella, Maria Teresa, van den Berg, Leonard H, Bockett, Nicholas A, de la Concha, Emilio G., Dema, Bárbara, Fehrmann, Rudolf SN, Fernández-Arquero, Miguel, Fiatal, Szilvia, Grandone, Elvira, Green, Peter M, Groen, Harry JM, Gwilliam, Rhian, Houwen, Roderick HJ, Hunt, Sarah E, Kaukinen, Katri, Kelleher, Dermot, Korponay-Szabo, Ilma, Kurppa, Kalle, MacMathuna, Padraic, Mäki, Markku, Mazzilli, Maria Cristina, McCann, Owen T, Mearin, M Luisa, Mein, Charles A, Mirza, Muddassar M, Mistry, Vanisha, Mora, Barbara, Morley, Katherine I, Mulder, Chris J, Murray, Joseph A, Núñez, Concepción, Oosterom, Elvira, Ophoff, Roel A, Polanco, Isabel, Peltonen, Leena, Platteel, Mathieu, Rybak, Anna, Salomaa, Veikko, Schweizer, Joachim J, Sperandeo, Maria Pia, Tack, Greetje J, Turner, Graham, Veldink, Jan H, Verbeek, Wieke HM, Weersma, Rinse K, Wolters, Victorien M, Urcelay, Elena, Cukrowska, Bozena, Greco, Luigi, Neuhausen, Susan L., McManus, Ross, Barisani, Donatella, Deloukas, Panos, Barrett, Jeffrey C, Saavalainen, Paivi, Wijmenga, Cisca, van Heel, David A
Publicat 2010

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

per Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J., Barrett, J., de Lane, K., Edwards, C., Hart, A., Hawkey, C., Jostins, L., Kennedy, N., Lamb, C., Lee, J., Lees, C., Mansfield, J., Mathew, C., Mowatt, C., Newman, B., Nimmo, E., Parkes, M., Pollard, M., Prescott, N., Randall, J., Rice, D., Satsangi, J., Simmons, A., Tremelling, M., Uhlig, H., Wilson, D., Abraham, C., Achkar, J. P., Bitton, A., Boucher, G., Croitoru, K., Fleshner, P., Glas, J., Kugathasan, S., Limbergen, J. V., Milgrom, R., Proctor, D., Regueiro, M., Schumm, P. L., Sharma, Y., Stempak, J. M., Targan, S. R., Wang, M. H.
Publicat a Nat Commun (2016)