Cathepsin L Inhibition Prevents Murine Autoimmune Diabetes via Suppression of CD8(+) T Cell Activity

per Yamada, Akiko, Ishimaru, Naozumi, Arakaki, Rieko, Katunuma, Nobuhiko, Hayashi, Yoshio
Publicat 2010

An Overview of Severe Acute Respiratory Syndrome–Coronavirus (SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule Chemotherapy

per Pillaiyar, Thanigaimalai, Manickam, Manoj, Namasivayam, Vigneshwaran, Hayashi, Yoshio, Jung, Sang-Hun
Publicat a J Med Chem (2016)

Analysis of in Vivo Role of α-Fodrin Autoantigen in Primary Sjögren’s Syndrome

per Miyazaki, Katsushi, Takeda, Noriaki, Ishimaru, Naozumi, Omotehara, Fumie, Arakaki, Rieko, Hayashi, Yoshio
Publicat 2005

Estrogen Deficiency Accelerates Autoimmune Exocrinopathy in Murine Sjögren’s Syndrome through Fas-Mediated Apoptosis

per Ishimaru, Naozumi, Saegusa, Kaoru, Yanagi, Kumiko, Haneji, Norio, Saito, Ichiro, Hayashi, Yoshio
Publicat 1999

Development of Autoimmune Exocrinopathy Resembling Sjögren’s Syndrome in Estrogen-Deficient Mice of Healthy Background

per Ishimaru, Naozumi, Arakaki, Rieko, Watanabe, Megumi, Kobayashi, Masaru, Miyazaki, Katsushi, Hayashi, Yoshio
Publicat 2003

Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome–like autoimmune exocrinopathy

per Ishimaru, Naozumi, Arakaki, Rieko, Yoshida, Satoko, Yamada, Akiko, Noji, Sumihare, Hayashi, Yoshio
Publicat 2008

Role of Plasmacytoid Dendritic Cells for Aberrant Class II Expression in Exocrine Glands from Estrogen-Deficient Mice of Healthy Background

per Arakaki, Rieko, Nagaoka, Ai, Ishimaru, Naozumi, Yamada, Akiko, Yoshida, Satoko, Hayashi, Yoshio
Publicat 2009

Slower immune system aging in women versus men in the Japanese population

per Hirokawa, Katsuiku, Utsuyama, Masanori, Hayashi, Yoshio, Kitagawa, Masanobu, Makinodan, Takashi, Fulop, Tamas
Publicat 2013

KPU-300, a Novel Benzophenone–Diketopiperazine–Type Anti-Microtubule Agent with a 2-Pyridyl Structure, Is a Potent Radiosensitizer That Synchronizes the Cell Cycle in Early M Phase...

per Okuyama, Kohei, Kaida, Atsushi, Hayashi, Yoshiki, Hayashi, Yoshio, Harada, Kiyoshi, Miura, Masahiko
Publicat a PLoS One (2015)

Structural Basis for the Effective Myostatin Inhibition of the Mouse Myostatin Prodomain-Derived Minimum Peptide

per Asari, Tomo, Takayama, Kentaro, Nakamura, Akari, Shimada, Takahiro, Taguchi, Akihiro, Hayashi, Yoshio
Publicat a ACS Med Chem Lett (2016)

Novel Role for RbAp48 in Tissue-Specific, Estrogen Deficiency-Dependent Apoptosis in the Exocrine Glands

per Ishimaru, Naozumi, Arakaki, Rieko, Omotehara, Fumie, Yamada, Koichi, Mishima, Kenji, Saito, Ichiro, Hayashi, Yoshio
Publicat 2006

In Situ Patrolling of Regulatory T Cells Is Essential for Protecting Autoimmune Exocrinopathy

per Ishimaru, Naozumi, Nitta, Takeshi, Arakaki, Rieko, Yamada, Akiko, Lipp, Martin, Takahama, Yousuke, Hayashi, Yoshio
Publicat 2010

Induction of Rapid T Cell Death and Phagocytic Activity by Fas-Deficient lpr Macrophages

per Oura, Ritsuko, Arakaki, Rieko, Yamada, Akiko, Kudo, Yasusei, Tanaka, Eiji, Hayashi, Yoshio, Ishimaru, Naozumi
Publicat 2013

New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors

per Regnier, Thomas, Sarma, Diganta, Hidaka, Koushi, Bacha, Usman, Freire, Ernesto, Hayashi, Yoshio, Kiso, Yoshiaki
Publicat a Bioorg Med Chem Lett (2009)

A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice

per Watanabe, Megumi, Ishimaru, Naozumi, Ashrin, Meinar Nur, Arakaki, Rieko, Yamada, Akiko, Ichikawa, Tetsuo, Hayashi, Yoshio
Publicat 2011

Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

per Saegusa, Kaoru, Ishimaru, Naozumi, Yanagi, Kumiko, Arakaki, Rieko, Ogawa, Kouichi, Saito, Ichiro, Katunuma, Nobuhiko, Hayashi, Yoshio
Publicat 2002

Severe Destructive Autoimmune Lesions with Aging in Murine Sjögren’s Syndrome through Fas-Mediated Apoptosis

per Ishimaru, Naozumi, Yoneda, Tomoko, Saegusa, Kaoru, Yanagi, Kumiko, Haneji, Norio, Moriyama, Keiji, Saito, Ichiro, Hayashi, Yoshio
Publicat 2000

Novel Hybrid-Type Antimicrobial Agents Targeting the Switch Region of Bacterial RNA Polymerase

per Yakushiji, Fumika, Miyamoto, Yuko, Kunoh, Yuki, Okamoto, Reiko, Nakaminami, Hidemasa, Yamazaki, Yuri, Noguchi, Norihisa, Hayashi, Yoshio
Publicat 2013

Structure–Activity Relationship Studies of 3-epi-Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates

per Hamada, Keisuke, Taguchi, Akihiro, Kotake, Masaya, Aita, Suguru, Murakami, Saori, Takayama, Kentaro, Yakushiji, Fumika, Hayashi, Yoshio
Publicat a ACS Med Chem Lett (2015)

Molecular Analysis of the Human Autoantibody Response to α-Fodrin in Sjögren’s Syndrome Reveals Novel Apoptosis-Induced Specificity

per Maruyama, Toshiaki, Saito, Ichiro, Hayashi, Yoshio, Kompfner, Elizabeth, Fox, Robert I., Burton, Dennis R., Ditzel, Henrik J.
Publicat 2004