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Cathepsin L Inhibition Prevents Murine Autoimmune Diabetes via Suppression of CD8(+) T Cell Activity
BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease resulting from defects in central and peripheral tolerance and characterized by T cell-mediated destruction of islet β cells. To determine whether specific lysosomal proteases might influence the outcome of a T cell–mediated autoimmune respo...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943924/ https://ncbi.nlm.nih.gov/pubmed/20877570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012894 |
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