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Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity
The cysteine endoprotease cathepsin S mediates degradation of the MHC class II invariant chain Ii in human and mouse antigen-presenting cells. Studies described here examine the functional significance of cathepsin S inhibition on autoantigen presentation and organ-specific autoimmune diseases in a...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151084/ https://ncbi.nlm.nih.gov/pubmed/12163455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14682 |
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