Severe Destructive Autoimmune Lesions with Aging in Murine Sjögren’s Syndrome through Fas-Mediated Apoptosis

When we evaluated the age-associated changes in autoimmune exocrinopathy in a NFS/sld murine model for primary Sjögren’s syndrome (SS), severe destructive autoimmune lesions developed in the salivary and lacrimal glands in the aged mice, compared with those observed in the younger model. We detected...

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Autores principales: Ishimaru, Naozumi, Yoneda, Tomoko, Saegusa, Kaoru, Yanagi, Kumiko, Haneji, Norio, Moriyama, Keiji, Saito, Ichiro, Hayashi, Yoshio
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2000
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876931/
https://ncbi.nlm.nih.gov/pubmed/10793067
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