Structural Development Studies of Subtype-Selective Ligands for Peroxisome Proliferator-Activated Receptors (PPARs) Based on the 3,4-Disubstituted Phenylpropanoic Acid Scaffold as...

por Miyachi, Hiroyuki, Hashimoto, Yuichi
Publicado em 2008

Cytosolic‐nuclear Tumor Promoter‐specific Binding Protein: Association with the 90 kDa Heat Shock Protein and Translocation into Nuclei by Treatment with 12‐O‐Tetradecanoylphorbol...

por Hashimoto, Yuichi, Shudo, Koichi
Publicado no Jpn J Cancer Res (1991)

Novel Heteroatom-containing Vitamin D(3) Analogs: Efficient Synthesis of 1α,25-Dihydroxyvitamin D(3)-26,23-lactam

por Kato, Yuko, Hashimoto, Yuichi, Nagasawa, Kazuo
Publicado no Molecules (2003)

Multiplexing fluorogenic esterase-based viability assay with luciferase assays

por Ohgane, Kenji, Yoshioka, Hiromasa, Hashimoto, Yuichi
Publicado no MethodsX (2019)

Specific Uptake of Retinoids into Human Promyelocytic Leukemia Cells HL‐60 by Retinoid‐specific Binding Protein: Possibly the True Retinoid Receptor

por Hashimoto, Yuichi, Kagechika, Hiroyuki, Kawachi, Emiko, Shudo, Koichi
Publicado no Jpn J Cancer Res (1988)

Humanin and Colivelin: Neuronal‐Death‐Suppressing Peptides for Alzheimer's Disease and Amyotrophic Lateral Sclerosis

por Matsuoka, Masaaki, Hashimoto, Yuichi, Aiso, Sadakazu, Nishimoto, Ikuo
Publicado no CNS Drug Rev (2006)

Humanin Inhibits Neuronal Cell Death by Interacting with a Cytokine Receptor Complex or Complexes Involving CNTF Receptor α/WSX-1/gp130

por Hashimoto, Yuichi, Kurita, Megumi, Aiso, Sadakazu, Nishimoto, Ikuo, Matsuoka, Masaaki
Publicado em 2009

SH3-binding Protein 5 Mediates the Neuroprotective Effect of the Secreted Bioactive Peptide Humanin by Inhibiting c-Jun NH(2)-terminal Kinase

por Takeshita, Yuji, Hashimoto, Yuichi, Nawa, Mikiro, Uchino, Hiroyuki, Matsuoka, Masaaki
Publicado em 2013

An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling

por Hashimoto, Yuichi, Toyama, Yuka, Kusakari, Shinya, Nawa, Mikiro, Matsuoka, Masaaki
Publicado no J Biol Chem (2016)

Efficient Lead Finding, Activity Enhancement and Preliminary Selectivity Control of Nuclear Receptor Ligands Bearing a Phenanthridinone Skeleton

por Nishiyama, Yuko, Fujii, Shinya, Makishima, Makoto, Hashimoto, Yuichi, Ishikawa, Minoru
Publicado no Int J Mol Sci (2018)

Distance from the external occipital protuberance to the occipital artery for occipital nerve block

por Arai, Takero, Ishikawa, Kazuyoshi, Saito, Tomoyuki, Hashimoto, Yuichi, Asai, Takashi, Okuda, Yasuhisa
Publicado em 2013

Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease

por Hashimoto, Yuichi, Kusakari, Shinya, Nawa, Mikiro, Okamoto, Koichi, Toyama, Yuka, Matsuoka, Masaaki
Publicado no Transl Psychiatry (2021)

Styrylphenylphthalimides as Novel Transrepression-Selective Liver X Receptor (LXR) Modulators

por Nomura, Sayaka, Endo-Umeda, Kaori, Aoyama, Atsushi, Makishima, Makoto, Hashimoto, Yuichi, Ishikawa, Minoru
Publicado no ACS Med Chem Lett (2015)

A novel tetramethylnaphthalene derivative synergistically inhibits HTLV-1-infected cell proliferation in combination with cepharanthine

por Hashimoto Yuichi, Okamoto Mika, Aoyama Hiroshi, Uto Tomofumi, Hamasaki Takayuki, Toyama Masaaki, Baba Masanori
Publicado em 2011-06-01

A novel tetramethylnaphthalene derivative synergistically inhibits HTLV-1-infected cell proliferation in combination with cepharanthine

por Toyama, Masaaki, Hamasaki, Takayuki, Uto, Tomofumi, Aoyama, Hiroshi, Okamoto, Mika, Hashimoto, Yuichi, Baba, Masanori
Publicado em 2011

A novel tetrahydrotetramethylbenzophenanthridinone derivative inhibits ATL cell proliferation

por Toyama, Masaaki, Takiguchi, Jun, Aoyama, Hiroshi, Yoshimura, Koji, Nakamura, Masaharu, Hashimoto, Yuichi, Baba, Masanori
Publicado em 2014

Novel Nonsteroidal Progesterone Receptor (PR) Antagonists with a Phenanthridinone Skeleton

por Nishiyama, Yuko, Mori, Shuichi, Makishima, Makoto, Fujii, Shinya, Kagechika, Hiroyuki, Hashimoto, Yuichi, Ishikawa, Minoru
Publicado no ACS Med Chem Lett (2018)

Improvement in aqueous solubility of achiral symmetric cyclofenil by modification to a chiral asymmetric analog

por Morimoto, Junki, Miyamoto, Kazunori, Ichikawa, Yuki, Uchiyama, Masanobu, Makishima, Makoto, Hashimoto, Yuichi, Ishikawa, Minoru
Publicado no Sci Rep (2021)

A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate

por Yoshioka, Hiromasa, Coates, Hudson W., Chua, Ngee Kiat, Hashimoto, Yuichi, Brown, Andrew J., Ohgane, Kenji
Publicado no Proc Natl Acad Sci U S A (2020)

Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative

por Ito, Wataru, Toyama, Masaaki, Okamoto, Mika, Ikeda, Masanori, Watashi, Koichi, Wakita, Takaji, Hashimoto, Yuichi, Baba, Masanori
Publicado no Antivir Chem Chemother (2016)