Humanin and Colivelin: Neuronal‐Death‐Suppressing Peptides for Alzheimer's Disease and Amyotrophic Lateral Sclerosis

Humanin (HN), a 24‐amino‐acid neuroprotective peptide, was originally found in the occipital lobe of an autopsied Alzheimer's disease (AD) patient. HN inhibits neuronal death by binding to its specific receptor on the cell membrane and triggering a Jak2/STAT3 prosurvival pathway. The activation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:CNS Drug Rev
Prif Awduron: Matsuoka, Masaaki, Hashimoto, Yuichi, Aiso, Sadakazu, Nishimoto, Ikuo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Inc 2006
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494132/
https://ncbi.nlm.nih.gov/pubmed/16958985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00113.x
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