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Humanin and Colivelin: Neuronal‐Death‐Suppressing Peptides for Alzheimer's Disease and Amyotrophic Lateral Sclerosis

Humanin (HN), a 24‐amino‐acid neuroprotective peptide, was originally found in the occipital lobe of an autopsied Alzheimer's disease (AD) patient. HN inhibits neuronal death by binding to its specific receptor on the cell membrane and triggering a Jak2/STAT3 prosurvival pathway. The activation...

詳細記述

保存先:
書誌詳細
出版年:CNS Drug Rev
主要な著者: Matsuoka, Masaaki, Hashimoto, Yuichi, Aiso, Sadakazu, Nishimoto, Ikuo
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Inc 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494132/
https://ncbi.nlm.nih.gov/pubmed/16958985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00113.x
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