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Humanin and Colivelin: Neuronal‐Death‐Suppressing Peptides for Alzheimer's Disease and Amyotrophic Lateral Sclerosis
Humanin (HN), a 24‐amino‐acid neuroprotective peptide, was originally found in the occipital lobe of an autopsied Alzheimer's disease (AD) patient. HN inhibits neuronal death by binding to its specific receptor on the cell membrane and triggering a Jak2/STAT3 prosurvival pathway. The activation...
保存先:
| 出版年: | CNS Drug Rev |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Inc
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494132/ https://ncbi.nlm.nih.gov/pubmed/16958985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2006.00113.x |
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