Oxidation of PAH trans-Dihydrodiols by Human Aldo-Keto Reductase AKR1B10

Por Quinn, Amy M., Harvey, Ronald G., Penning, Trevor M.
Publicado em 2008

Synthesis of Phenol and Quinone Metabolites of Benzo[a]pyrene, a Carcinogenic Component of Tobacco Smoke Implicated in Lung Cancer

Por Xu, Daiwang, Penning, Trevor M., Blair, Ian A., Harvey, Ronald G.
Publicado em 2009

Quantitation of Benzo[a]pyrene Metabolic Profiles in Human Bronchoalveolar H358) Cells by Stable Isotope Dilution Liquid Chromatography-Atmospheric Chemical Ionization Mass Spectro...

Por Lu, Ding, Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2011

PAH o-quinones produced by the Aldo-Keto-Reductases (AKRs) generate abasic sites, oxidized pyrimidines and 8-oxo-dGuo via reactive oxygen species

Por Park, Jong-Heum, Troxel, Andrea B., Harvey, Ronald G., Penning, Trevor M.
Publicado em 2006

Regulation of Benzo[a]pyrene-Mediated DNA- and Glutathione-Adduct Formation by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Lung Cells

Por Gelhaus, Stacy L., Harvey, Ronald G., Penning, Trevor M., Blair, Ian A.
Publicado em 2010

Regiospecific oxidation of polycyclic aromatic phenols to quinones by hypervalent iodine reagents

Por Wu, Anhui, Duan, Yazhen, Xu, Daiwang, Penning, Trevor M., Harvey, Ronald G.
Publicado em 2010

Topics in phosphorus chemistry /

Por Austin, T. Howard, Berlin, K. Darrel, De Sombre, Eugene R., Harvey, Ronald G., Grayson, Martin
Publicado em 1964

Synthesis of (13)C(2)-Benzo[a]pyrene and its 7,8-Dihydrodiol and 7,8-Dione Implicated as Carcinogenic Metabolites

Por Ran, Chongzhao, Xu, Daiwang, Dai, Qing, Penning, Trevor M., Blair, Ian A, Harvey, Ronald G.
Publicado em 2008

Synthesis of (13)C(4)-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene

Por Wu, Anhui, Xu, Daiwang, Lu, Ding, Penning, Trevor M., Blair, Ian A., Harvey, Ronald G.
Publicado em 2012

Metabolism of Benzo[a]pyrene in Human Bronchoalveolar H358 Cells Using Liquid Chromatography-Mass Spectrometry

Por Jiang, Hao, Gelhaus, Stacy L., Mangal, Dipti, Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2007

Fjord-region Benzo[g]chrysene-11,12-dihydrodiol and Benzo[c]phenanthrene-3,4-dihydrodiol as Substrates for Rat Liver Dihydrodiol Dehydrogenase (AKR1C9): Structural Basis for Stereo...

Por Shultz, Carol A., Palackal, Nisha T., Mangal, Dipti, Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2008

Formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dGuo) by PAH o-quinones: involvement of reactive oxygen species and copper(II)/copper(I) redox cycling

Por Park, Jong-Heum, Gopishetty, Sridhar, Szewczuk, Lawrence M., Troxel, Andrea B., Harvey, Ronald G., Penning, Trevor M.
Publicado em 2005

Aryl Hydrocarbon Receptor Facilitates DNA Strand Breaks and 8-Oxo-2′-deoxyguanosine Formation by the Aldo-Keto Reductase Product Benzo[a]pyrene-7,8-dione

Por Park, Jong-Heum, Mangal, Dipti, Frey, Alexander J., Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2009

Detoxication of Structurally Diverse Polycyclic Aromatic Hydrocarbon (PAH) o-Quinones by Human Recombinant Catechol-O-methyltransferase (COMT) via O-Methylation of PAH Catechols

Por Zhang, Li, Jin, Yi, Chen, Mo, Huang, Meng, Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2011

Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells

Por Park, Jong-Heum, Mangal, Dipti, Tacka, Kirk A., Quinn, Amy M., Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2008

Specificity of Human Aldo-Keto Reductases, NAD(P)H: Quinone Oxidoreductase and Carbonyl Reductases to Redox-Cycle Polycyclic Aromatic Hydrocarbon Diones and 4-Hydroxyequilenin-o-Qu...

Por Shultz, Carol A., Quinn, Amy M., Park, Jong-Heum, Harvey, Ronald G., Bolton, Judy L, Maser, Edmund, Penning, Trevor M.
Publicado em 2011

Metabolism and Distribution of Benzo[a]pyrene-7,8-dione (B[a]P-7,8-dione) in Human Lung Cells by Liquid Chromatography Tandem Mass Spectrometry: Detection of an Adenine B[a]P-7,8-d...

Por Huang, Meng, Liu, Xiaojing, Basu, Sankha S., Zhang, Li, Kushman, Mary E., Harvey, Ronald G., Blair, Ian A., Penning, Trevor M.
Publicado em 2012