Synthesis of (13)C(2)-Benzo[a]pyrene and its 7,8-Dihydrodiol and 7,8-Dione Implicated as Carcinogenic Metabolites

Synthesis of the (13)C(2)-labelled analogues of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene and its active metabolites are described. The method entails Pd-catalyzed Suzuki-Miyaura coupling of a naphthalene boronic acid with 2-bromobenzene-1,3-dialdehyde followed by Wittig reacti...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ran, Chongzhao, Xu, Daiwang, Dai, Qing, Penning, Trevor M., Blair, Ian A, Harvey, Ronald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804341/
https://ncbi.nlm.nih.gov/pubmed/24155502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2008.05.033
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky