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Oxidation of PAH trans-Dihydrodiols by Human Aldo-Keto Reductase AKR1B10

AKR1B10 has been identified as a potential biomarker for human non-small cell lung carcinoma and as a tobacco exposure and response gene. AKR1B10 functions as an efficient retinal reductase in vitro, and may regulate retinoic acid homeostasis. However, the possibility that this enzyme is able to act...

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Detalhes bibliográficos
Main Authors: Quinn, Amy M., Harvey, Ronald G., Penning, Trevor M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645959/
https://ncbi.nlm.nih.gov/pubmed/18788756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx8002005
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