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Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review
INTRODUCTION: AKR1C3 is a drug target in hormonal and hormonal independent malignancies and acts as a major peripheral 17β-hydroxysteroid dehydrogenase to yield the potent androgens testosterone and dihydrotestosterone, and as a prostaglandin (PG) F synthase to produce proliferative ligands for the...
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| Veröffentlicht in: | Expert Opin Ther Pat |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724044/ https://ncbi.nlm.nih.gov/pubmed/28895472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543776.2017.1379503 |
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