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Role of Aldo-Keto Reductase Family 1 (AKR1) Enzymes in Human Steroid Metabolism
Human aldo-keto reductases AKR1C1-AKR1C4 and AKR1D1 play essential roles in the metabolism of all steroid hormones, the biosynthesis of neurosteroids and bile acids, the metabolism of conjugated steroids, and synthetic therapeutic steroids. These enzymes catalyze NADPH dependent reductions at the C3...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870468/ https://ncbi.nlm.nih.gov/pubmed/24189185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2013.10.012 |
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