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Aldo-Keto Reductases and Cancer Drug Resistance
Human aldo-keto reductases (AKRs) catalyze the NADPH-dependent reduction of carbonyl groups to alcohols for conjugation reactions to proceed. They are implicated in resistance to cancer chemotherapeutic agents either because they are directly involved in their metabolism or help eradicate the cellul...
में बचाया:
| में प्रकाशित: | Pharmacol Rev |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8318518/ https://ncbi.nlm.nih.gov/pubmed/34312303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pharmrev.120.000122 |
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