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Aldo-Keto Reductases and Cancer Drug Resistance
Human aldo-keto reductases (AKRs) catalyze the NADPH-dependent reduction of carbonyl groups to alcohols for conjugation reactions to proceed. They are implicated in resistance to cancer chemotherapeutic agents either because they are directly involved in their metabolism or help eradicate the cellul...
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| Publicat a: | Pharmacol Rev |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8318518/ https://ncbi.nlm.nih.gov/pubmed/34312303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pharmrev.120.000122 |
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