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Aldo-Keto Reductases and Cancer Drug Resistance

Human aldo-keto reductases (AKRs) catalyze the NADPH-dependent reduction of carbonyl groups to alcohols for conjugation reactions to proceed. They are implicated in resistance to cancer chemotherapeutic agents either because they are directly involved in their metabolism or help eradicate the cellul...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmacol Rev
मुख्य लेखकों: Penning, Trevor M., Jonnalagadda, Sravan, Trippier, Paul C., Rižner, Tea Lanišnik
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318518/
https://ncbi.nlm.nih.gov/pubmed/34312303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pharmrev.120.000122
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