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Steroid Hormone Transforming Aldo-Keto Reductases and Cancer

Prostate and breast cancer are hormone dependent malignancies of the aging male and female and require the local production of androgens and estrogens to stimulate cell proliferation. Aldo-keto reductases (AKR) play key roles in this process. In the prostate, AKR1C3 (type 5 17β-HSD) reduces Δ(4)-and...

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Autores principales: Penning, Trevor M., Byrns, Michael C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038333/
https://ncbi.nlm.nih.gov/pubmed/19250190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.03700.x
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