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Steroid Hormone Transforming Aldo-Keto Reductases and Cancer

Prostate and breast cancer are hormone dependent malignancies of the aging male and female and require the local production of androgens and estrogens to stimulate cell proliferation. Aldo-keto reductases (AKR) play key roles in this process. In the prostate, AKR1C3 (type 5 17β-HSD) reduces Δ(4)-and...

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Bibliografiska uppgifter
Huvudupphovsmän: Penning, Trevor M., Byrns, Michael C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038333/
https://ncbi.nlm.nih.gov/pubmed/19250190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.03700.x
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