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Structural and Functional Biology of Aldo-Keto Reductase Steroid-Transforming Enzymes
Aldo-keto reductases (AKRs) are monomeric NAD(P)(H)-dependent oxidoreductases that play pivotal roles in the biosynthesis and metabolism of steroids in humans. AKR1C enzymes acting as 3-ketosteroid, 17-ketosteroid, and 20-ketosteroid reductases are involved in the prereceptor regulation of ligands f...
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| Publicado no: | Endocr Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6405412/ https://ncbi.nlm.nih.gov/pubmed/30137266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/er.2018-00089 |
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