Загрузка...
Selective Inhibitors of Aldo-Keto Reductases AKR1C1 and AKR1C3 Discovered by Virtual Screening of a Fragment Library
Human aldo-keto reductases 1C1-1C4 (AKR1C1-AKR1C4) function in vivo as 3-keto-, 17-keto- and 20- ketosteroid reductases, and regulate the activity of androgens, estrogens and progesterone and the occupancy and transactivation of their corresponding receptors. Aberrant expression and action of AKR1C...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3470935/ https://ncbi.nlm.nih.gov/pubmed/22881866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300841n |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|