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Synthesis of (13)C(4)-labelled oxidized metabolites of the carcinogenic polycyclic aromatic hydrocarbon benzo[a]pyrene

Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), are ubiquitous environmental contaminants that are implicated in causing lung cancer. BaP is a component of tobacco smoke that is transformed enzymatically to active forms that interact with DNA. We reported previously developmen...

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Hlavní autoři: Wu, Anhui, Xu, Daiwang, Lu, Ding, Penning, Trevor M., Blair, Ian A., Harvey, Ronald G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826453/
https://ncbi.nlm.nih.gov/pubmed/24244053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.05.130
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