Direct Subunit-Dependent Multimodal 5-Hydroxytryptamine(3) Receptor Antagonism by Methadone

Por Deeb, Tarek Z., Sharp, Douglas, Hales, Tim G.
Publicado em 2009

Loop G in the GABA(A) receptor α1 subunit influences gating efficacy

Por Baptista‐Hon, Daniel T., Gulbinaite, Simona, Hales, Tim G.
Publicado no J Physiol (2017)

Modulation by general anaesthetics of rat GABA(A) receptors comprised of α1β3 and β3 subunits expressed in human embryonic kidney 293 cells

Por Davies, Paul A, Kirkness, Ewen F, Hales, Tim G
Publicado em 1997

Evidence for the formation of functionally distinct αβγε GABA(A) receptors

Por Davies, Paul A, Kirkness, Ewen F, Hales, Tim G
Publicado em 2001

A role for loop G in the β1 strand in GABA(A) receptor activation

Por Baptista‐Hon, Daniel T., Krah, Alexander, Zachariae, Ulrich, Hales, Tim G.
Publicado no J Physiol (2016)

δ Receptors Are Required for Full Inhibitory Coupling of μ Receptors to Voltage-Dependent Ca(2+) Channels in Dorsal Root Ganglion Neurons

Por Walwyn, Wendy, John, Scott, Maga, Matthew, Evans, Christopher J., Hales, Tim G.
Publicado em 2009

Agonist- and antagonist-induced up-regulation of surface 5-HT(3)A receptors

Por Morton, Russell A, Baptista-Hon, Daniel T, Hales, Tim G, Lovinger, David M
Publicado no Br J Pharmacol (2015)

High Affinity Binding of Epibatidine to Serotonin Type 3 Receptors

Por Drisdel, Renaldo C., Sharp, Douglas, Henderson, Tricia, Hales, Tim G., Green, William N.
Publicado em 2008

Fluorophore assisted light inactivation (FALI) of recombinant 5-HT(3)A receptor constitutive internalization and function

Por Morton, Russell A., Luo, Guoxiang, Davis, Margaret I., Hales, Tim G., Lovinger, David M.
Publicado em 2011

The 5-HT3B subunit affects high-potency inhibition of 5-HT(3) receptors by morphine

Por Baptista-Hon, Daniel T, Deeb, Tarek Z, Othman, Nidaa A, Sharp, Douglas, Hales, Tim G
Publicado em 2012

Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src

Por Bull, Fiona A., Baptista-Hon, Daniel T., Lambert, Jeremy J., Walwyn, Wendy, Hales, Tim G.
Publicado no Sci Rep (2017)

The Minimum M3-M4 Loop Length of Neurotransmitter-activated Pentameric Receptors Is Critical for the Structural Integrity of Cytoplasmic Portals

Por Baptista-Hon, Daniel T., Deeb, Tarek Z., Lambert, Jeremy J., Peters, John A., Hales, Tim G.
Publicado em 2013

Src Kinase Inhibition Attenuates Morphine Tolerance without Affecting Reinforcement or Psychomotor Stimulation

Por Bull, Fiona A., Baptista-Hon, Daniel T., Sneddon, Claire, Wright, Lisa, Walwyn, Wendy, Hales, Tim G.
Publicado no Anesthesiology (2017)

A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT(3) receptor function

Por Wu, Dai-Fei, Othman, Nidaa A, Sharp, Douglas, Mahendra, Arjun, Deeb, Tarek Z, Hales, Tim G
Publicado em 2010

Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2

Por Lam, Hoa, Maga, Matthew, Pradhan, Amynah, Evans, Christopher J, Maidment, Nigel T, Hales, Tim G, Walwyn, Wendy
Publicado em 2011

Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization

Por Othman, Nidaa A, Gallacher, Michael, Deeb, Tarek Z, Baptista-Hon, Daniel T, Perry, David C, Hales, Tim G
Publicado em 2012

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors

Por Peters, John A, Cooper, Michelle A, Carland, Jane E, Livesey, Matthew R, Hales, Tim G, Lambert, Jeremy J
Publicado em 2010

Mutagenic Analysis of the Intracellular Portals of the Human 5-HT(3)A Receptor

Por Carland, Jane E., Cooper, Michelle A., Livesey, Matthew R., Hales, Tim G., Peters, John A., Lambert, Jeremy J.
Publicado em 2013

Structural Determinants of Ca(2+) Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor

Por Livesey, Matthew R., Cooper, Michelle A., Deeb, Tarek Z., Carland, Jane E., Kozuska, Janna, Hales, Tim. G., Lambert, Jeremy J., Peters, John A.
Publicado em 2008

Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion

Por House, Carrie D., Vaske, Charles J., Schwartz, Arnold M., Obias, Vincent, Frank, Bryan, Luu, Truong, Sarvazyan, Narine, Irby, Rosalyn, Strausberg, Robert L., Hales, Tim G., Stuart, Joshua M., Lee, Norman H.
Publicado em 2010