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Loop G in the GABA(A) receptor α1 subunit influences gating efficacy
KEY POINTS: The functional importance of residues in loop G of the GABA(A) receptor has not been investigated. D43 and T47 in the α1 subunit are of particular significance as their structural modification inhibits activation by GABA. While the T47C substitution had no significant effect, non‐conserv...
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| Publicado no: | J Physiol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330932/ https://ncbi.nlm.nih.gov/pubmed/27981574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273752 |
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