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Loop G in the GABA(A) receptor α1 subunit influences gating efficacy
KEY POINTS: The functional importance of residues in loop G of the GABA(A) receptor has not been investigated. D43 and T47 in the α1 subunit are of particular significance as their structural modification inhibits activation by GABA. While the T47C substitution had no significant effect, non‐conserv...
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| Опубликовано в: : | J Physiol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330932/ https://ncbi.nlm.nih.gov/pubmed/27981574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273752 |
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