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Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization
NON-TECHNICAL SUMMARY: The convulsant t-butylbicyclophosphorothionate (TBPS) is considered a GABA(A) receptor (GABA(A)R) open channel blocker. However, the relationship between the functional state of the receptor and TBPS binding remains unclear. Radiolabelled [(35)S]TBPS binds to GABA(A)Rs in the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3300054/ https://ncbi.nlm.nih.gov/pubmed/22083597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.213249 |
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