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The 5-HT3B subunit affects high-potency inhibition of 5-HT(3) receptors by morphine

BACKGROUND AND PURPOSE: Morphine is an antagonist at 5-HT(3)A receptors. 5-HT(3) and opioid receptors are expressed in many of the same neuronal pathways where they modulate gut motility, pain and reinforcement. There is increasing interest in the 5-HT3B subunit, which confers altered pharmacology t...

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Detalhes bibliográficos
Main Authors: Baptista-Hon, Daniel T, Deeb, Tarek Z, Othman, Nidaa A, Sharp, Douglas, Hales, Tim G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315041/
https://ncbi.nlm.nih.gov/pubmed/21740409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01582.x
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