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Agonist- and antagonist-induced up-regulation of surface 5-HT(3)A receptors

BACKGROUND AND PURPOSE: The 5-HT(3) receptor is a member of the pentameric ligand-gated ion channel family and is pharmacologically targeted to treat irritable bowel syndrome and nausea/emesis. Furthermore, many antidepressants elevate extracellular concentrations of 5-HT. This study investigates th...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Morton, Russell A, Baptista-Hon, Daniel T, Hales, Tim G, Lovinger, David M
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4543613/
https://ncbi.nlm.nih.gov/pubmed/25989383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13197
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