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Agonist- and antagonist-induced up-regulation of surface 5-HT(3)A receptors
BACKGROUND AND PURPOSE: The 5-HT(3) receptor is a member of the pentameric ligand-gated ion channel family and is pharmacologically targeted to treat irritable bowel syndrome and nausea/emesis. Furthermore, many antidepressants elevate extracellular concentrations of 5-HT. This study investigates th...
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Publicado no: | Br J Pharmacol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4543613/ https://ncbi.nlm.nih.gov/pubmed/25989383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13197 |
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