5-HT3 receptor antagonism by anpirtoline, a mixed 5-HT1 receptor agonist/5-HT3 receptor antagonist.

1. The aim of this study was to provide evidence that anpirtoline, which is an agonist at 5-HT1B and 5-HT1D receptors and also displays submicromolar affinity for 5-HT1A recognition sites, in addition, acts as an antagonist at 5-HT3 receptors. 2. In radioligand binding studies on rat brain cortical...

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Main Authors: Göthert, M, Hamon, M, Barann, M, Bönisch, H, Gozlan, H, Laguzzi, R, Metzenauer, P, Nickel, B, Szelenyi, I
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510248/
https://ncbi.nlm.nih.gov/pubmed/7881726
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