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Direct inhibition by cannabinoids of human 5-HT(3A) receptors: probable involvement of an allosteric modulatory site

1. Excised outside-out patches from HEK293 cells stably transfected with the human (h) 5-HT(3A) receptor cDNA were used to determine the effects of cannabinoid receptor ligands on the 5-HT-induced current using the patch clamp technique. In addition, binding studies with radioligands for 5-HT(3) as...

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Detalhes bibliográficos
Main Authors: Barann, M, Molderings, G, Brüss, M, Bönisch, H, Urban, B W, Göthert, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573528/
https://ncbi.nlm.nih.gov/pubmed/12381672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704829
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