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5-HT(2) Receptor Regulation of Mitochondrial Genes: Unexpected Pharmacological Effects of Agonists and Antagonists

In acute organ injuries, mitochondria are often dysfunctional, and recent research has revealed that recovery of mitochondrial and renal functions is accelerated by induction of mitochondrial biogenesis (MB). We previously reported that the nonselective 5-HT(2) receptor agonist DOI [1-(4-iodo-2,5-di...

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Pubblicato in:J Pharmacol Exp Ther
Autori principali: Harmon, Jennifer L., Wills, Lauren P., McOmish, Caitlin E., Demireva, Elena Y., Gingrich, Jay A., Beeson, Craig C., Schnellmann, Rick G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809314/
https://ncbi.nlm.nih.gov/pubmed/26787771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.228395
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