The 5-HT(4) receptor agonist, tegaserod, is a potent 5-HT(2B) receptor antagonist in vitro and in vivo

1. Tegaserod (Zelnorm®) is a potent 5-hydroxytryptamine(4) (5-HT(4)) receptor agonist with clinical efficacy in disorders associated with reduced gastrointestinal motility and transit. The present study investigated the interaction of tegaserod with 5-HT(2) receptors, and compared its potency in thi...

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Detalhes bibliográficos
Main Authors: Beattie, D T, Smith, J A M, Marquess, D, Vickery, R G, Armstrong, S R, Pulido-Rios, T, McCullough, J L, Sandlund, C, Richardson, C, Mai, N, Humphrey, P P A
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575425/
https://ncbi.nlm.nih.gov/pubmed/15466450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705929
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