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Effect of the 5-HT(4) receptor agonist tegaserod on the expression of GRK2 and GRK6 in the rat gastrointestinal tract
OBJECTIVE: Tegaserod is a 5-hydroxytryptamine type 4 (5-HT(4)) receptor agonist, formerly used in treating constipation predominant irritable bowel syndrome, which desensitizes 5-HT(4) receptors in rat oesophagus and colon in vitro. Desensitization of 5-HT(4) receptors is regulated by G-protein coup...
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| Опубликовано в: : | BMC Res Notes |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5994065/ https://ncbi.nlm.nih.gov/pubmed/29884229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-018-3495-2 |
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