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Human 5–HT(4) and 5–HT(7) Receptor Splice Variants: Are they Important?

G-protein-coupled receptors (GPCRs), which are encoded by >300 genes in the human genome, are by far the largest class of targets for modern drugs. These macromolecules display inherent adaptability of function, which is partly due to the production of different forms of the receptor protein. The...

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Détails bibliographiques
Auteurs principaux: Coupar, Ian M, Desmond, Paul V, Irving, Helen R
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers Ltd. 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644495/
https://ncbi.nlm.nih.gov/pubmed/19305739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157015907782793621
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