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Modulation by general anaesthetics of rat GABA(A) receptors comprised of α1β3 and β3 subunits expressed in human embryonic kidney 293 cells

1. Radioligand binding and patch-clamp techniques were used to study the actions of γ-aminobutyric acid (GABA) and the general anaesthetics propofol (2,6-diisopropylphenol), pentobarbitone and 5α-pregnan-3α-ol-20-one on rat α1 and β3 GABA(A) receptor subunits, expressed either alone or in combinatio...

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Detalhes bibliográficos
Main Authors: Davies, Paul A, Kirkness, Ewen F, Hales, Tim G
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564547/
https://ncbi.nlm.nih.gov/pubmed/9138697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700987
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