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β-Arrestin2 and c-Src Regulate the Constitutive Activity and Recycling of μ Opioid Receptors in Dorsal Root Ganglion Neurons

β-Arrestins bind to agonist-activated G-protein-coupled receptors regulating signaling events and initiating endocytosis. In β-arrestin2(−/−) (βarr2(−/−)) mice, a complex phenotype is observed that includes altered sensitivity to morphine. However, little is known of how β-arrestin2 affects μ recept...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Walwyn, Wendy, Evans, Christopher J., Hales, Tim G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672367/
https://ncbi.nlm.nih.gov/pubmed/17494695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1157-07.2007
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