Regulation of Wnt/β‐catenin signalling by tankyrase‐dependent poly(ADP‐ribosyl)ation and scaffolding

Por Mariotti, Laura, Pollock, Katie, Guettler, Sebastian
Publicado no Br J Pharmacol (2017)

Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL

Por Posern, Guido, Miralles, Francesc, Guettler, Sebastian, Treisman, Richard
Publicado em 2004

RPEL Motifs Link the Serum Response Factor Cofactor MAL but Not Myocardin to Rho Signaling via Actin Binding

Por Guettler, Sebastian, Vartiainen, Maria K., Miralles, Francesc, Larijani, Banafshe, Treisman, Richard
Publicado em 2008

Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL

Por Mouilleron, Stephane, Guettler, Sebastian, Langer, Carola A, Treisman, Richard, McDonald, Neil Q
Publicado em 2008

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling

Por Mariotti, Laura, Templeton, Catherine M., Ranes, Michael, Paracuellos, Patricia, Cronin, Nora, Beuron, Fabienne, Morris, Edward, Guettler, Sebastian
Publicado no Mol Cell (2016)

Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function

Por Persaud, Avinash, Alberts, Philipp, Hayes, Madeline, Guettler, Sebastian, Clarke, Ian, Sicheri, Frank, Dirks, Peter, Ciruna, Brian, Rotin, Daniela
Publicado em 2011

Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation

Por Xiong, Shawn, Couzens, Amber L., Kean, Michelle J., Mao, Daniel Y., Guettler, Sebastian, Kurinov, Igor, Gingras, Anne-Claude, Sicheri, Frank
Publicado no Mol Cell Proteomics (2017)

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

Por Couzens, Amber L., Xiong, Shawn, Knight, James D. R., Mao, Daniel Y., Guettler, Sebastian, Picaud, Sarah, Kurinov, Igor, Filippakopoulos, Panagis, Sicheri, Frank, Gingras, Anne-Claude
Publicado no Mol Cell Proteomics (2017)

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Por Pettitt, Stephen J., Krastev, Dragomir B., Brandsma, Inger, Dréan, Amy, Song, Feifei, Aleksandrov, Radoslav, Harrell, Maria I., Menon, Malini, Brough, Rachel, Campbell, James, Frankum, Jessica, Ranes, Michael, Pemberton, Helen N., Rafiq, Rumana, Fenwick, Kerry, Swain, Amanda, Guettler, Sebastian, Lee, Jung-Min, Swisher, Elizabeth M., Stoynov, Stoyno, Yusa, Kosuke, Ashworth, Alan, Lord, Christopher J.
Publicado no Nat Commun (2018)