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Regulation of Wnt/β‐catenin signalling by tankyrase‐dependent poly(ADP‐ribosyl)ation and scaffolding

The Wnt/β‐catenin signalling pathway is pivotal for stem cell function and the control of cellular differentiation, both during embryonic development and tissue homeostasis in adults. Its activity is carefully controlled through the concerted interactions of concentration‐limited pathway components...

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Bibliographic Details
Published in:Br J Pharmacol
Main Authors: Mariotti, Laura, Pollock, Katie, Guettler, Sebastian
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727255/
https://ncbi.nlm.nih.gov/pubmed/28910490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14038
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