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Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL
Nuclear accumulation of the serum response factor coactivator MAL/MKL1 is controlled by its interaction with G-actin, which results in its retention in the cytoplasm in cells with low Rho activity. We previously identified actin mutants whose expression promotes MAL nuclear accumulation via an unkno...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC524340/ https://ncbi.nlm.nih.gov/pubmed/15385960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600404 |
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