Redox Potential Control by Drug Binding to Cytochrome P450 3A4

por Das, Aditi, Grinkova, Yelena V., Sligar, Stephen G.
Publicado 2007

Engineering extended membrane scaffold proteins for self-assembly of soluble nanoscale lipid bilayers

por Grinkova, Yelena V., Denisov, Ilia G., Sligar, Stephen G.
Publicado 2010

Functional reconstitution of monomeric CYP3A4 with multiple cytochrome P450 reductase molecules in Nanodiscs

por Grinkova, Yelena V., Denisov, Ilia G., Sligar, Stephen G.
Publicado 2010

The Critical Iron-Oxygen Intermediate in Human Aromatase

por Gantt, Stephanie L., Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G.
Publicado 2009

Oxidase uncoupling in heme monoxygenases: Human cytochrome P450 CYP3A4 in Nanodiscs

por Grinkova, Yelena V., Denisov, Ilia G., McLean, Mark A., Sligar, Stephen G.
Publicado 2012

Dark, Ultra-Dark and Ultra-Bright Nanodiscs for membrane protein investigations

por McLean, Mark A., Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G.
Publicado en Anal Biochem (2020)

Kinetic Solvent Isotope Effect in Human P450 CYP17A1 Mediated Androgen Formation: Evidence for a Reactive Peroxoanion Intermediate

por Gregory, Michael C., Denisov, Ilia G., Grinkova, Yelena V., Khatri, Yogan, Sligar, Stephen G.
Publicado 2013

Active site proton delivery and the lyase activity of human CYP17A1

por Khatri, Yogan, Gregory, Michael C., Grinkova, Yelena V., Denisov, Ilia G., Sligar, Stephen G.
Publicado 2013

Mechanism of Drug-Drug Interactions Mediated by Human Cytochrome P450 CYP3A4 Monomer

por Denisov, Ilia G., Grinkova, Yelena V., Baylon, Javier L., Tajkhorshid, Emad, Sligar, Stephen G.
Publicado en Biochemistry (2015)

Drug-drug interactions between Atorvastatin and Dronedarone mediated by monomeric CYP3A4

por Denisov, Ilia G., Baylon, Javier L., Grinkova, Yelena V., Tajkhorshid, Emad, Sligar, Stephen G.
Publicado en Biochemistry (2017)

Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions

por Ivanova, Lada, Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G., Fæste, Christiane K.
Publicado en Metabolites (2019)

Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian Cytochrome P450

por Mak, Piotr J., Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G., Kincaid, James R.
Publicado 2011

Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213

por Denisov, Ilia G., Grinkova, Yelena V., Nandigrami, Prithviraj, Shekhar, Mrinal, Tajkhorshid, Emad, Sligar, Stephen G.
Publicado en Biochemistry (2019)

The Ferrous-Oxy Complex of Human Aromatase

por Grinkova, Yelena V., Denisov, Ilia G., Waterman, Michael R., Arase, Miharu, Kagawa, Norio, Sligar, Stephen G.
Publicado 2008

Thermotropic phase transition in soluble nanoscale lipid bilayers

por Denisov, Ilia G., McLean, Mark A., Shaw, Andrew W., Grinkova, Yelena V., Sligar, Stephen G.
Publicado 2005

Nanodiscs as a therapeutic delivery agent: inhibition of respiratory syncytial virus infection in the lung

por Numata, Mari, Grinkova, Yelena V, Mitchell, James R, Chu, Hong Wei, Sligar, Stephen G, Voelker, Dennis R
Publicado 2013

Stretching DNA using the Electric Field in a Synthetic Nanopore

por Heng, Jiunn B., Aksimentiev, Aleksei, Ho, Chuen, Marks, Patrick, Grinkova, Yelena V., Sligar, Steve, Schulten, Klaus, Timp, Gregory
Publicado 2005

The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4

por Denisov, Ilia G., Mak, Piotr J., Grinkova, Yelena V., Bastien, Dominic, Bérubé, Gervais, Sligar, Stephen G., Kincaid, James R.
Publicado en J Inorg Biochem (2015)

Sizing DNA Using a Nanometer-Diameter Pore

por Heng, Jiunn B., Ho, Chuen, Kim, Taekyung, Timp, Rolf, Aksimentiev, Aleksij, Grinkova, Yelena V., Sligar, Stephen, Schulten, Klaus, Timp, Gregory
Publicado 2004

Incorporation of Charged Residues in the CYP2J2 F-G Loop Disrupts CYP2J2-Lipid Bilayer Interactions

por McDougle, Daniel R., Baylon, Javier L., Meling, Daryl D., Kambalyal, Amogh, Grinkova, Yelena V., Hammernik, Jared, Tajkhorshid, Emad, Das, Aditi
Publicado en Biochim Biophys Acta (2015)