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Active site proton delivery and the lyase activity of human CYP17A1
Cytochrome P450 CYP17A1 catalyzes a series of reactions that lie at the intersection of corticoid and androgen biosynthesis and thus occupies an essential role in steroid hormone metabolism. This multifunctional enzyme catalyzes the 17α-hydroxylation of Δ4- and Δ5-steroids progesterone and pregnenol...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912944/ https://ncbi.nlm.nih.gov/pubmed/24299954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.11.094 |
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