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Oxidase uncoupling in heme monoxygenases: Human cytochrome P450 CYP3A4 in Nanodiscs

The normal reaction mechanism of cytochrome P450 operates by utilizing two reducing equivalents to reduce atmospheric dioxygen, producing one molecule of water and an oxygenated product in an overall stoichiometry of 2 electrons : 1 dioxygen : 1 product. However, three alternate unproductive pathway...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Grinkova, Yelena V., Denisov, Ilia G., McLean, Mark A., Sligar, Stephen G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191626/
https://ncbi.nlm.nih.gov/pubmed/23266608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.12.072
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