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Oxidase uncoupling in heme monoxygenases: Human cytochrome P450 CYP3A4 in Nanodiscs
The normal reaction mechanism of cytochrome P450 operates by utilizing two reducing equivalents to reduce atmospheric dioxygen, producing one molecule of water and an oxygenated product in an overall stoichiometry of 2 electrons : 1 dioxygen : 1 product. However, three alternate unproductive pathway...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191626/ https://ncbi.nlm.nih.gov/pubmed/23266608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.12.072 |
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