Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: Implications for normal aging and age-dependent neurodegenerative disorders

Por Graziotto, John J, Cao, Kan, Collins, Francis S, Krainc, Dimitri
Publicado em 2012

Mitochondrial Parkin Recruitment Is Impaired in Neurons Derived from Mutant PINK1 Induced Pluripotent Stem Cells

Por Seibler, Philip, Graziotto, John, Jeong, Hyun, Simunovic, Filip, Klein, Christine, Krainc, Dimitri
Publicado em 2011

Temporal and Tissue Specific Regulation of RP-Associated Splicing Factor Genes PRPF3, PRPF31 and PRPC8—Implications in the Pathogenesis of RP

Por Cao, Huibi, Wu, Jing, Lam, Simon, Duan, Rongqi, Newnham, Catherine, Molday, Robert S., Graziotto, John J., Pierce, Eric A., Hu, Jim
Publicado em 2011

Three Gene-Targeted Mouse Models of RNA Splicing Factor RP Show Late-Onset RPE and Retinal Degeneration

Por Graziotto, John J., Farkas, Michael H., Bujakowska, Kinga, Deramaudt, Bertrand M., Zhang, Qi, Nandrot, Emeline F., Inglehearn, Chris F., Bhattacharya, Shomi S., Pierce, Eric A.
Publicado em 2011

Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

Por Chung, Sun Young, Kishinevsky, Sarah, Mazzulli, Joseph R., Graziotto, John, Mrejeru, Ana, Mosharov, Eugene V., Puspita, Lesly, Valiulahi, Parvin, Sulzer, David, Milner, Teresa A., Taldone, Tony, Krainc, Dimitri, Studer, Lorenz, Shim, Jae-won
Publicado no Stem Cell Reports (2016)

Familial Parkinson's disease iPSCs show cellular deficits in mitochondrial responses that can be pharmacologically rescued

Por Cooper, Oliver, Seo, Hyemyung, Andrabi, Shaida, Guardia-Laguarta, Cristina, Graziotto, John, Sundberg, Maria, McLean, Jesse R., Carrillo-Reid, Luis, Xie, Zhong, Osborn, Teresia, Hargus, Gunnar, Deleidi, Michela, Lawson, Tristan, Bogetofte, Helle, Perez-Torres, Eduardo, Clark, Lorraine, Moskowitz, Carol, Mazzulli, Joseph, Chen, Li, Volpicelli-Daley, Laura, Romero, Norma, Jiang, Houbo, Uitti, Ryan J., Huang, Zhigao, Opala, Grzegorz, Scarffe, Leslie A., Dawson, Valina L., Klein, Christine, Feng, Jian, Ross, Owen A., Trojanowski, John Q., Lee, Virginia M.-Y., Marder, Karen, Surmeier, D. James, Wszolek, Zbigniew K., Przedborski, Serge, Krainc, Dimitri, Dawson, Ted M., Isacson, Ole
Publicado em 2012