Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson’s disease brain regions and in a transgenic mouse model of alp...

Por McLean, Jesse R., Hallett, Penelope J., Cooper, Oliver, Stanley, Michael, Isacson, Ole
Publicado em 2011

Alpha-synuclein overexpressing transgenic mice show internal organ pathology and autonomic deficits

Por Hallett, Penelope J, McLean, Jesse R, Kartunen, Andrew, Langston, J. William, Isacson, Ole
Publicado em 2012

An Aggregate-Inducing Peripherin Isoform Generated through Intron Retention Is Upregulated in Amyotrophic Lateral Sclerosis and Associated with Disease Pathology

Por Xiao, Shangxi, Tjostheim, Sonja, Sanelli, Teresa, McLean, Jesse R., Horne, Patrick, Fan, Yuxin, Ravits, John, Strong, Michael J., Robertson, Janice
Publicado no J Neurosci (2008)

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

Por Smith, Gaynor A., Rocha, Emily M., Rooney, Thomas, Barneoud, Pascal, McLean, Jesse R., Beagan, Jonathan, Osborn, Teresia, Coimbra, Madeleine, Luo, Yongyi, Hallett, Penelope J., Isacson, Ole
Publicado no PLoS One (2015)

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

Por Rocha, Emily M., Smith, Gaynor A., Park, Eric, Cao, Hongmei, Graham, Anne-Renee, Brown, Eilish, McLean, Jesse R., Hayes, Melissa A., Beagan, Jonathan, Izen, Sarah C., Perez-Torres, Eduardo, Hallett, Penelope J., Isacson, Ole
Publicado no Antioxid Redox Signal (2015)

Jump from Pre-mutation to Pathologic Expansion in C9orf72

Por Xi, Zhengrui, van Blitterswijk, Marka, Zhang, Ming, McGoldrick, Philip, McLean, Jesse R., Yunusova, Yana, Knock, Erin, Moreno, Danielle, Sato, Christine, McKeever, Paul M., Schneider, Raphael, Keith, Julia, Petrescu, Nicolae, Fraser, Paul, Tartaglia, Maria Carmela, Baker, Matthew C., Graff-Radford, Neill R., Boylan, Kevin B., Dickson, Dennis W., Mackenzie, Ian R., Rademakers, Rosa, Robertson, Janice, Zinman, Lorne, Rogaeva, Ekaterina
Publicado no Am J Hum Genet (2015)

Familial Parkinson's disease iPSCs show cellular deficits in mitochondrial responses that can be pharmacologically rescued

Por Cooper, Oliver, Seo, Hyemyung, Andrabi, Shaida, Guardia-Laguarta, Cristina, Graziotto, John, Sundberg, Maria, McLean, Jesse R., Carrillo-Reid, Luis, Xie, Zhong, Osborn, Teresia, Hargus, Gunnar, Deleidi, Michela, Lawson, Tristan, Bogetofte, Helle, Perez-Torres, Eduardo, Clark, Lorraine, Moskowitz, Carol, Mazzulli, Joseph, Chen, Li, Volpicelli-Daley, Laura, Romero, Norma, Jiang, Houbo, Uitti, Ryan J., Huang, Zhigao, Opala, Grzegorz, Scarffe, Leslie A., Dawson, Valina L., Klein, Christine, Feng, Jian, Ross, Owen A., Trojanowski, John Q., Lee, Virginia M.-Y., Marder, Karen, Surmeier, D. James, Wszolek, Zbigniew K., Przedborski, Serge, Krainc, Dimitri, Dawson, Ted M., Isacson, Ole
Publicado em 2012