Negative Regulation of Protein Translation by Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2

di Knauf, Ursula, Tschopp, Claude, Gram, Hermann
Pubblicazione 2001

Biomarkers in Systemic Juvenile Idiopathic Arthritis: A comparison with biomarkers in Cryopyrin Associated Periodic Syndromes

di Nirmala, Nanguneri, Grom, Alexei, Gram, Hermann
Pubblicato in Curr Opin Rheumatol (2014)

The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β

di Rondeau, Jean-Michel, Ramage, Paul, Zurini, Mauro, Gram, Hermann
Pubblicato in MAbs (2015)

Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5′-Terminal Cap and Hairpin

di Korneeva, Nadejda L., Song, Anren, Gram, Hermann, Edens, Mary Ann, Rhoads, Robert E.
Pubblicato in J Biol Chem (2016)

Neutralization of Interleukin-1β following Diffuse Traumatic Brain Injury in the Mouse Attenuates the Loss of Mature Oligodendrocytes

di Flygt, Johanna, Ruscher, Karsten, Norberg, Amanda, Mir, Anis, Gram, Hermann, Clausen, Fredrik, Marklund, Niklas
Pubblicato in J Neurotrauma (2018)

Pharmacokinetic and Pharmacodynamic Properties of Canakinumab, a Human Anti-Interleukin-1β Monoclonal Antibody

di Chakraborty, Abhijit, Tannenbaum, Stacey, Rordorf, Christiane, Lowe, Philip J., Floch, David, Gram, Hermann, Roy, Sandip
Pubblicazione 2012

Combination therapy for treating advanced drug-resistant acute lymphoblastic leukemia

di Vicioso, Yorleny, Gram, Hermann, Beck, Rose, Asthana, Abhishek, Zhang, Keman, Wong, Derek P., Letterio, John, Parameswaran, Reshmi
Pubblicato in Cancer Immunol Res (2019)

Regulation of the MEF2 Family of Transcription Factors by p38

di Zhao, Ming, New, Liguo, Kravchenko, Vladimir V., Kato, Yutaka, Gram, Hermann, di Padova, Franco, Olson, Eric N., Ulevitch, Richard J., Han, Jiahuai
Pubblicazione 1999

Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis

di Denes, Adam, Drake, Caroline, Stordy, Jing, Chamberlain, Janet, McColl, Barry W., Gram, Hermann, Crossman, David, Francis, Sheila, Allan, Stuart M., Rothwell, Nancy J.
Pubblicazione 2012

Effector-mediated eradication of precursor B acute lymphoblastic leukemia with a novel Fc engineered monoclonal antibody targeting the BAFF-R

di Parameswaran, Reshmi, Lim, Min, Fei, Fei, Abdel-Azim, Hisham, Arutyunyan, Anna, Schiffer, Isabelle, McLaughlin, Margaret E., Gram, Hermann, Huet, Heather, Groffen, John, Heisterkamp, Nora
Pubblicazione 2014

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis

di Vromman, Amélie, Ruvkun, Victoria, Shvartz, Eugenia, Wojtkiewicz, Gregory, Santos Masson, Gustavo, Tesmenitsky, Yevgenia, Folco, Eduardo, Gram, Hermann, Nahrendorf, Matthias, Swirski, Filip K, Sukhova, Galina K, Libby, Peter
Pubblicato in Eur Heart J (2019)

Inhibition of Polysome Assembly Enhances Imatinib Activity against Chronic Myelogenous Leukemia and Overcomes Imatinib Resistance

di Zhang, Min, Fu, Wuxia, Prabhu, Sharmila, Moore, James C., Ko, Je, Kim, Jung Woo, Druker, Brian J., Trapp, Valerie, Fruehauf, John, Gram, Hermann, Fan, Hung Y., Ong, S. Tiong
Pubblicazione 2008

Therapeutic Administration of a Monoclonal Anti-Il-1β Antibody Protects Against Experimental Melioidosis

di Weehuizen, Tassili A. F., Lankelma, Jacqueline M., De Jong, Hanna K., De Boer, Onno J., Roelofs, Joris J. T. H., Day, Nicholas P., Gram, Hermann, De Vos, Alex F., Wiersinga, W. Joost
Pubblicato in Shock (2016)

An Activating Janus Kinase-3 Mutation Is Associated with Cytotoxic T Lymphocyte Antigen-4-Dependent Immune Dysregulation Syndrome

di Sic, Heiko, Speletas, Matthaios, Cornacchione, Vanessa, Seidl, Maximillian, Beibel, Martin, Linghu, Bolan, Yang, Fan, Sevdali, Eirini, Germenis, Anastasios E., Oakeley, Edward J., Vangrevelinghe, Eric, Sailer, Andreas W., Traggiai, Elisabetta, Gram, Hermann, Eibel, Hermann
Pubblicato in Front Immunol (2017)

Blocking of Interleukin-17 during Reactivation of Experimental Arthritis Prevents Joint Inflammation and Bone Erosion by Decreasing RANKL and Interleukin-1

di Koenders, Marije I., Lubberts, Erik, Oppers-Walgreen, Birgitte, van den Bersselaar, Liduine, Helsen, Monique M., Di Padova, Franco E., Boots, Annemieke M.H., Gram, Hermann, Joosten, Leo A.B., van den Berg, Wim B.
Pubblicazione 2005

Interleukin-1β promotes atheroprotective changes of advanced atherosclerotic lesions in mice

di Gomez, Delphine, Baylis, Richard A., Durgin, Brittany G., Newman, Alexandra A. C., Alencar, Gabriel F., Mahan, Sidney, St. Hilaire, Cynthia, Muller, Werner, Waisman, Ari, Francis, Sheila E., Pinteaux, Emmanuel, Randolph, Gwendalyn J., Gram, Hermann, Owens, Gary K.
Pubblicato in Nat Med (2018)

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

di Alten, Rieke, Gram, Hermann, Joosten, Leo A, Berg, Wim B van den, Sieper, Joachim, Wassenberg, Siegfrid, Burmester, Gerd, van Riel, Piet, Diaz-Lorente, Maria, Bruin, Gerardus JM, Woodworth, Thasia G, Rordorf, Christiane, Batard, Yannik, Wright, Andrew M, Jung, Thomas
Pubblicazione 2008

Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

di Brachat, Arndt H., Grom, Alexei A., Wulffraat, Nico, Brunner, Hermine I., Quartier, Pierre, Brik, Riva, McCann, Liza, Ozdogan, Huri, Rutkowska-Sak, Lidia, Schneider, Rayfel, Gerloni, Valeria, Harel, Liora, Terreri, Maria, Houghton, Kristin, Joos, Rik, Kingsbury, Daniel, Lopez-Benitez, Jorge M., Bek, Stephan, Schumacher, Martin, Valentin, Marie-Anne, Gram, Hermann, Abrams, Ken, Martini, Alberto, Lovell, Daniel J., Nirmala, Nanguneri R., Ruperto, Nicolino
Pubblicato in Arthritis Res Ther (2017)