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The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β
Interleukin-1β (IL-1β) plays a key role in autoinflammatory diseases, such as systemic juvenile idiopathic arthritis (sJIA) or cryopyrin-associated periodic syndrome (CAPS). Canakinumab, a human monoclonal anti-IL-1β antibody, was recently approved for human use under the brand name Ilaris®. Canakin...
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| Publicado no: | MAbs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966334/ https://ncbi.nlm.nih.gov/pubmed/26284424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1081323 |
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