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Dry Eye Signs and Symptoms Persist During Systemic Neutralization of IL-1β by Canakinumab or IL-17A by Secukinumab

To evaluate whether inhibition of the proinflammatory cytokines IL-1β or IL-17A by canakinumab or secukinumab, respectively, influence the signs and symptoms of dry eye. METHODS: In a randomized, double-masked, placebo-controlled, outpatient clinical trial, 72 patients with moderate to severe dry ey...

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Detalhes bibliográficos
Publicado no:Cornea
Main Authors: Grosskreutz, Cynthia L., Hockey, Hans-Ulrich, Serra, Denise, Dryja, Thaddeus P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cornea 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633966/
https://ncbi.nlm.nih.gov/pubmed/26418434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000000627
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