Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis

AIMS: Targeting interleukin-1 (IL-1) represents a novel therapeutic approach to atherosclerosis. CANTOS demonstrated the benefits of IL-1β neutralization in patients post-myocardial infarction with residual inflammatory risk. Yet, some mouse data have shown a prominent role of IL-1α rather than IL-1...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Vromman, Amélie, Ruvkun, Victoria, Shvartz, Eugenia, Wojtkiewicz, Gregory, Santos Masson, Gustavo, Tesmenitsky, Yevgenia, Folco, Eduardo, Gram, Hermann, Nahrendorf, Matthias, Swirski, Filip K, Sukhova, Galina K, Libby, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685323/
https://ncbi.nlm.nih.gov/pubmed/30698710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz008
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