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Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling
AIMS: Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms α and β) have impaired expansive arterial remodeling due to diminished expression of matrix-degrading enzymes, especially MMP-3. Emergence of IL-1 as a target in cardiovascular disease prompted the investigation of the...
Tallennettuna:
| Julkaisussa: | PLoS One |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816548/ https://ncbi.nlm.nih.gov/pubmed/27032103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152474 |
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